Weight and metabolism
The best-researched peptides of all, tested in studies with thousands of people.
- How much weight do people lose?
In the largest studies, participants lost on average about 15 per cent with semaglutide and up to 21 per cent with tirzepatide. In the highest dose group for retatrutide, the figure was 25 per cent.
- How do these medicines work?
They mimic hormones the gut releases after a meal, such as GLP-1 and GIP. These hormones help you feel full and help the body control blood sugar.
- Do the benefits go beyond weight?
Yes. In a study of more than 17,000 people, fewer had a heart attack or stroke or died of cardiovascular disease on semaglutide. With retatrutide, knee pain in osteoarthritis and breathing pauses in sleep apnoea went down.
- How do I get one of these medicines?
Talk to your doctor. With a prescription, you collect semaglutide or tirzepatide at a pharmacy or order from an approved Norwegian online pharmacy.
- RetatrutideLarge human trials
- SemaglutideLarge human trials
- TirzepatideLarge human trials
- MOTS-cLab and animal studies


